Buy PE-22-28 10mg: VND price and studies
Buy PE-22-28 10mg: PE-22-28 10mg is a seven amino acid peptide trimmed from spadin, a natural blocker of the TREK-1 channel, for 2,300,000 VND ($90 USD) a vial.
It was built in a 2017 study in Frontiers in Pharmacology, and its research so far is mouse work and a 2019 review, with both studies from one team in France.
2,300,000 VND ($90 USD)
Price for 1 vial
USD prices are the store's dollar prices; you pay the VND price.
Quantity
- Free tracked delivery to Da Nang in 1 to 3 days.
- Comes with bacteriostatic water and a container.
- Research use only. Not an approved medicine, and nothing here is medical advice.
What PE-22-28 is
Spadin itself is a 17 amino acid fragment cut from a larger protein, sortilin. TREK-1, the channel it shuts, lets potassium move through nerve cells. PE-22-28 keeps a seven amino acid section of spadin, and a 2017 study compared how strongly the two shut TREK-1.
The work comes from one team in Valbonne, France, at a national research institute for molecular and cell pharmacology.
What have PE-22-28 and spadin been tested in?
Spadin was first described in a 2010 mouse study, which ran mice through 5 standard behavior tests of the kind used to screen possible antidepressants.
In 2017 the same team built PE-22-28 from spadin and put it through similar mouse tests. A 2019 review covered spadin and its shortened versions, including how quickly spadin itself is broken down. The 2010 tests were a broad screen, but still only a screen.
PE-22-28 is not an antidepressant or any approved medicine, and no country has cleared it for use in people.
Sources: 2010 spadin study in mice, PMID 20405001; 2017 study that built PE-22-28, PMID 28955242; 2019 review, PMID 30291907.
What mouse behavior tests can and cannot show
Tests like the forced swim test are screening tools that researchers use to sort compounds. A score there does not show that anything would happen in a person, and our search found no study of PE-22-28 in people. The 2010 and 2017 studies both come from one team in Valbonne.
Want to save on PE-22-28 10mg with a pack?
| Pack | Per mg | Each vial | You pay |
|---|---|---|---|
| Single vial | 230,000 VND ($9 USD) | 2,300,000 VND ($90 USD) | 2,300,000 VND ($90 USD) |
| Pack of 3 | 186,300 VND ($7.29 USD) | 1,863,000 VND ($72.90 USD) | 5,589,000 VND ($218.70 USD) |
| Pack of 5 | 165,600 VND ($6.48 USD) | 1,656,000 VND ($64.80 USD) | 8,280,000 VND ($324 USD) |
| Pack of 10 | 138,000 VND ($5.40 USD) | 1,380,000 VND ($54 USD) | 13,800,000 VND ($540 USD) |
Got more questions about PE-22-28?
Is PE-22-28 the same as spadin?
No. Spadin has 17 amino acids, and PE-22-28 is a seven amino acid section made from it.
Has PE-22-28 been tested in people?
No study in people was found. The research here is two mouse studies from one team in France and a 2019 review.
What is TREK-1?
A potassium channel in nerve cells. Spadin and PE-22-28 shut it, and that is how they are studied in mouse behavior tests.
Where was PE-22-28 developed?
In Valbonne, France, by the team that first described spadin.
Where does spadin come from?
It is a 17 amino acid fragment cut from a larger protein called sortilin.
What is PE 22-28 peptide?
A seven amino acid peptide cut down from spadin, which blocks the TREK-1 channel. One French team has studied it, mostly in mouse behavior tests.
What does PE-22-28 cost?
PE-22-28 is sold at 2,300,000 VND ($90 USD) a vial. That works out to 230,000 VND ($9 USD) per mg of PE-22-28, and a five pack makes each vial 1,656,000 VND ($64.80 USD).